貨號
產品規格
售價
備注
BN42057M-50ul
50ul
￥1620.00
交叉反應（總）:Human, ;推薦應用:IHC-P,
BN42057M-100ul
100ul
￥2440.00
交叉反應（總）:Human, ;推薦應用:IHC-P,
產品描述
| 英文名稱 | MUC6 |
| 中文名稱 | 粘蛋白6單克隆抗體 |
| 別 名 | Gastric mucin 6 ; Gastric Mucin ; Gastric mucin-6 ; MUC 6 ; MUC-6 ; Muc6 ; MUC6 Fragment ; MUC6 mucin ; MUC6 mucin Fragment ; MUC6_HUMAN ; Mucin 6 ; Mucin 6 gastric ; Mucin 6 oligomeric mucus/gel forming ; Mucin glycoprotein Fragment ; Mucin-6 ; Secretory mucin MUC6 Fragment . |
| 研究領域 | 腫瘤 細胞生物 細胞骨架 細胞外基質 |
| 抗體來源 | Mouse |
| 克隆類型 | Monoclonal |
| 克 隆 號 | 6H8 |
| 交叉反應 | Human, |
| 產品應用 | IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 298kDa |
| 細胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MUC6: |
| 亞 型 | IgG2a |
| 純化方法 | affinity purified by Protein G |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 產品介紹 | This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. [provided by RefSeq, Dec 2016] Function: May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Play an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis. Subcellular Location: Secreted. Tissue Specificity: Expressed in the regenerative zone of gastric antrum, gastric body mucosa and gastric incisura mucosa. Expressed in the deeper mucous glands of gastric antrum. Overexpressed in Helicobacter pylori infected gastric epithelium. Highly expressed in duodenal Brunner's glands, gall bladder, seminal vesicle, pancreatic centroacinar cells and ducts, and periductal glands of the common bile duct. Post-translational modifications: O-glycosylated. Similarity: Contains 1 CTCK (C-terminal cystine knot-like) domain. Contains 1 TIL (trypsin inhibitory-like) domain. Contains 3 VWFD domains. SWISS: Q6W4X9 Gene ID: 4588 Database links:
Entrez Gene: 353328 Mouse Omim: 158374 Human SwissProt: Q6W4X9 Human SwissProt: Q80T03 Mouse Unigene: 528432 Human Unigene: 246621 Mouse Unigene: 92457 Rat Important Note: |
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