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周期素A1蛋白抗體
  • 產(chǎn)品貨號：
    BN40683R
  • 中文名稱(chēng)：
    周期素A1蛋白抗體
  • 英文名稱(chēng)：
    Rabbit anti-Cyclin A1 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規格

    售價(jià)

    備注

  • BN40683R-100ul

    100ul

    ￥2120.00

    交叉反應（總）:Hu Mo Rat Cow Rab Sheep ;推薦應用:WB,

  • BN40683R-200ul

    200ul

    ￥3140.00

    交叉反應（總）:Hu Mo Rat Cow Rab Sheep ;推薦應用:WB,

產(chǎn)品描述

英文名稱(chēng)Cyclin A1
中文名稱(chēng)周期素A1蛋白抗體
研究領(lǐng)域腫瘤  免疫學(xué)  細胞周期蛋白  
抗體來(lái)源Rabbit
克隆類(lèi)型Polyclonal
交叉反應Mouse, Rat,  (predicted: Human, Cow, Rabbit, Sheep, )
產(chǎn)品應用WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量51kDa
細胞定位細胞核 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human Cyclin A1 :391-465/465 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹Cyclin A1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin A1 is expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. It binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. Cyclin A1 was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins.

Function:
Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions.

Subcellular Location:
Nucleus. Cytoplasm. Cytoplasmic when associated with SCAPER.

Similarity:
Belongs to the cyclin family. Cyclin AB subfamily.

SWISS:
P78396

Gene ID:
8900

Database links:

Entrez Gene: 8900 Human

Entrez Gene: 12427 Mouse

Omim: 604036 Human

SwissProt: P78396 Human

SwissProt: Q61456 Mouse

Unigene: 417050 Human

Unigene: 4815 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.